Invention Application
US20160207988A1 A NOVEL HORMONE THAT PROMOTES BONE RESORPTION AND USES THEREOF
审中-公开
一种促进骨骼再生的新型激素及其用途
- Patent Title: A NOVEL HORMONE THAT PROMOTES BONE RESORPTION AND USES THEREOF
- Patent Title (中): 一种促进骨骼再生的新型激素及其用途
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Application No.: US15024357Application Date: 2014-09-23
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Publication No.: US20160207988A1Publication Date: 2016-07-21
- Inventor: Yihong WAN
- Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
- Applicant Address: US TX Austin
- Assignee: The Board of Regents of the University of Texas System
- Current Assignee: The Board of Regents of the University of Texas System
- Current Assignee Address: US TX Austin
- International Application: PCT/US14/56934 WO 20140923
- Main IPC: C07K16/18
- IPC: C07K16/18 ; A61K45/06 ; A61K38/18

Abstract:
The disclosure describes the use of anti-IGFBP1 antibodies to inhibit the bone loss-inducing properties of FGF21. This can be applied in the context of FGF21 treatment for obesity and/or diabetes, or in menopause-induced bone loss, such as osteoporosis.
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