Invention Application
- Patent Title: IL-17RA-IL-17RB Antagonists and Uses Thereof
- Patent Title (中): IL-17RA-IL-17RB拮抗剂及其用途
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Application No.: US14994108Application Date: 2016-01-12
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Publication No.: US20160208004A1Publication Date: 2016-07-21
- Inventor: Alison L. Budelsky , Michael R. Comeau , Joel E. Tocker
- Applicant: AMGEN INC.
- Main IPC: C07K16/28
- IPC: C07K16/28
Abstract:
The present invention relates to Interleukin-17 ligand and receptor family members and the discovery that IL-17 receptor A and IL-17 receptor C form a heteromeric receptor complex that is biologically active. Antagonists of the IL-17RA-IL-17RB heteromeric receptor complex are disclosed, as well as various methods of use.
Information query
