Invention Application
US20160229872A1 ISOTHIAZOLOPYRIMIDINONES, PYRAZOLOPYRIMIDINONES, AND PYRROLOPYRIMIDINONES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS
有权
异亮氨酸嘧啶酮，吡唑并嘧啶酮和吡咯烷二酮作为UBIQUITIN特异性蛋白酶7抑制剂
- Patent Title: ISOTHIAZOLOPYRIMIDINONES, PYRAZOLOPYRIMIDINONES, AND PYRROLOPYRIMIDINONES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS
- Patent Title (中): 异亮氨酸嘧啶酮，吡唑并嘧啶酮和吡咯烷二酮作为UBIQUITIN特异性蛋白酶7抑制剂
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Application No.: US15015566Application Date: 2016-02-04
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Publication No.: US20160229872A1Publication Date: 2016-08-11
- Inventor: Stephanos Ioannidis , Adam Charles Talbot , Bruce Follows , Alexandre Joseph Buckmelter , Minghua Wang , Ann-Marie Campbell
- Applicant: Forma Therapeutics, Inc.
- Main IPC: C07D513/04
- IPC: C07D513/04 ; C07D487/04
Abstract:
The disclosure relates to inhibitors of USP7 inhibitors useful in the treatment of cancers, neurodegenerative diseases, immunological disorders, inflammatory disorders, cardiovascular diseases, ischemic diseases, viral infections and diseases, and bacterial infections and diseases, having the Formula: where R1, R2, R3, R4, R5, R5′, X1, X2, X3, n, and m are described herein.
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