A compound oral cleaning device includes a first main body, configured with a control circuit, electric power storage unit and driving element in electric connection with each other in sequence at a center thereof; and a second main body, capable of being coupled to the first main body optionally, and a rotating element coupled to said driving element being configured at a center of the second main body. Whereby, the present invention can clean slits between teeth and fur on tongue effectively, and can further carry out the replacement of the rotating element, having both cuticle removing and skin whitening effects after being replaced with a skin rubbing tool.