A Chinese medicine capable of triggering lung adenocarcinoma cell autophagy mainly uses a polygala tenuifolia willd herb with a quantity depending on a patient's physical fitness and sickness conditions determined by a doctor, and capable of triggering a lung adenocarcionma cell autophagy (cracking) to achieve a treatment effect. Regardless of being taken as a powder or an extract, the medicine is capable of triggering the adenocarcionma cell autophagy (cracking) effect to achieve the treatment effect. The polygala tenuifolia willd applies a new protein transport mode as a target enzyme screening to successfully prove the effect of triggering lung adenocarcionma cell autophagy (cracking) for cancer treatment.