Invention Application
- Patent Title: Tau Antisense Oligomers and Uses Thereof
- Patent Title (中): Tau反义寡聚体及其用途
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Application No.: US15016169Application Date: 2016-02-04
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Publication No.: US20160237427A1Publication Date: 2016-08-18
- Inventor: Richard E. OLSON , Angela M. CACACE , Peter HAGEDORN , Anja Mølhart HØG , Marianne Lerbech JENSEN , Niels Fisker NIELSEN , Dong LI , Jeffrey M. BROWN , Stephen E. MERCER
- Applicant: Bristol-Myers Squibb Company , Roche Innovation Center Copenhagen A/S
- Main IPC: C12N15/113
- IPC: C12N15/113
Abstract:
The present invention relates to oligomer compounds (oligomers), which target Tau mRNA in a cell, leading to reduced expression of Tau protein. Reduction of Tau protein expression is beneficial for the treatment of certain medical disorders, e.g., a neurological disorder.
Public/Granted literature
- US10799523B2 Tau antisense oligomers and uses thereof Public/Granted day:2020-10-13
Information query
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