发明申请
- 专利标题： Tau Antisense Oligomers and Uses Thereof
- 专利标题（中）： Tau反义寡聚体及其用途
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申请号： US15016169申请日： 2016-02-04
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公开(公告)号： US20160237427A1公开(公告)日： 2016-08-18
- 发明人: Richard E. OLSON , Angela M. CACACE , Peter HAGEDORN , Anja Mølhart HØG , Marianne Lerbech JENSEN , Niels Fisker NIELSEN , Dong LI , Jeffrey M. BROWN , Stephen E. MERCER
- 申请人： Bristol-Myers Squibb Company , Roche Innovation Center Copenhagen A/S
- 主分类号： C12N15/113
- IPC分类号： C12N15/113
摘要：
The present invention relates to oligomer compounds (oligomers), which target Tau mRNA in a cell, leading to reduced expression of Tau protein. Reduction of Tau protein expression is beneficial for the treatment of certain medical disorders, e.g., a neurological disorder.
公开/授权文献
- US10799523B2 Tau antisense oligomers and uses thereof 公开/授权日：2020-10-13
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