发明申请
- 专利标题: METHOD FOR GENERATION OF BROADLY NEUTRALIZING ANTI-PATHOGEN ANTIBODIES
- 专利标题(中): 广泛中和抗病原体抗体的方法
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申请号: US14777605申请日: 2014-03-18
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公开(公告)号: US20160250248A1公开(公告)日: 2016-09-01
- 发明人: Michail V. SITKOVSKY , Robert Koehler ABBOTT , Stephen Matthew HATFIELD
- 申请人: Northeastern University
- 国际申请: PCT/US2014/031104 WO 20140318
- 主分类号: A61K31/7076
- IPC分类号: A61K31/7076 ; C12N5/0781 ; A61K45/06 ; A61K39/39
摘要:
Methods and composition for potentiating germinal centers are disclosed herein. The methods include potentiating germinal centers to enhance antibody production in response to a vaccine, to increase antibody titer in response to a vaccine, and to enhance B cell class switching.
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