A clothes structure with temperature falling device is provided, which has a fan provided in a low-permeability layer outside a clothes major body, and an air delivery space provided between the low-permeability layer and a lining layer inside. When the fan sucks the air from the outside of the clothes major body through air intake end and delivers the air to the inside of the clothes major body, air will flow uniformly in the air delivery space and to everywhere in the clothes major body. Then proper quantity of uniform air flow is output from an inner lining layer with meshes to everywhere of user's body to make user feeling cool and comfortable.