Invention Application
US20160271214A1 METHODS OF TREATING HEART FAILURE WITH AGONISTS OF HYPOCRETIN RECEPTOR 2
审中-公开
高血压受体激动剂治疗心力衰竭的方法2
- Patent Title: METHODS OF TREATING HEART FAILURE WITH AGONISTS OF HYPOCRETIN RECEPTOR 2
- Patent Title (中): 高血压受体激动剂治疗心力衰竭的方法2
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Application No.: US15037030Application Date: 2014-11-13
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Publication No.: US20160271214A1Publication Date: 2016-09-22
- Inventor: Euan A. Ashley , Marco V. Perez
- Applicant: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
- International Application: PCT/US2014/065519 WO 20141113
- Main IPC: A61K38/17
- IPC: A61K38/17 ; C12Q1/68 ; A61K45/06
Abstract:
Methods of treating individuals for heart failure are disclosed. In particular, the invention relates to methods of treating individuals for heart failure with agonists of hypocretin receptor 2. The invention further relates to the use of genetic analysis of the single nucleotide polymorphism rs7767652, which resides immediately upstream of the HCRTR2 gene, to identify individuals in need of treatment for heart failure who are predicted to be more responsive to medical intervention.
Public/Granted literature
- US10172916B2 Methods of treating heart failure with agonists of hypocretin receptor 2 Public/Granted day:2019-01-08
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