发明申请
US20160279232A1 Gene-Deleted Variant Strain Of Porcine Pseudorabies Virus, Vaccine Composition, Method Of Making The Same And Use Thereof
审中-公开
猪伪狂犬病病毒的基因缺失变异株，疫苗组成，制作方法和使用方法
- 专利标题： Gene-Deleted Variant Strain Of Porcine Pseudorabies Virus, Vaccine Composition, Method Of Making The Same And Use Thereof
- 专利标题（中）： 猪伪狂犬病病毒的基因缺失变异株，疫苗组成，制作方法和使用方法
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申请号： US15054404申请日： 2016-02-26
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公开(公告)号： US20160279232A1公开(公告)日： 2016-09-29
- 发明人: Kegong TIAN , Xuke ZHANG , Jinzhong SUN , Feifei TAN
- 申请人： Pulike Biological Engineering, Inc.
- 优先权： CN201410418379.8 20140822
- 主分类号： A61K39/245
- IPC分类号： A61K39/245 ; C12N7/00
摘要：
The present invention provides an attenuated strain of porcine pseudorabies virus (PRV), in which said attenuated strain of PRV is a variant strain of PRV with inactivation of gI/gE/11K/28K proteins. In addition, the present invention also provides a vaccine composition comprising the attenuated strain of PRV as an antigen, a preparation method and use thereof. Proved by immunogenicity and pathogenicity testing of the live vaccine, said live PRV vaccine can provide a good protection for pigs with no clinical signs observed, indicating excellent immune protection.
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