Invention Application
US20160297795A1 Tetrahydrobenzimidazole Derivatives as Modulators of TNF Activity
审中-公开
四氢苯并咪唑衍生物作为TNF活性的调节剂
- Patent Title: Tetrahydrobenzimidazole Derivatives as Modulators of TNF Activity
- Patent Title (中): 四氢苯并咪唑衍生物作为TNF活性的调节剂
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Application No.: US15038287Application Date: 2014-12-08
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Publication No.: US20160297795A1Publication Date: 2016-10-13
- Inventor: Jag Paul Heer , Victoria Elizabeth Jackson , Boris Kroeplien , Fabien Claude Lecomte , John Robert Porter
- Applicant: UCB BIOPHARMA SPRL
- Priority: GB1321744.3 20131209
- International Application: PCT/EP2014/076854 WO 20141208
- Main IPC: C07D401/10
- IPC: C07D401/10 ; A61K31/4439
Abstract:
A series of substituted 4,5,6,7-tetrahydrobenzimidazole derivatives, being potent modulators of human TNFα activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.
Public/Granted literature
- US10093652B2 Tetrahydrobenzimidazole derivatives as modulators of TNF activity Public/Granted day:2018-10-09
Information query
