发明申请
- 专利标题: SOLUBLE GUANYLATE CYCLASE ACTIVATORS
- 专利标题(中): 可溶性冠状动脉激素
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申请号: US15103148申请日: 2014-12-05
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公开(公告)号: US20160304537A1公开(公告)日: 2016-10-20
- 发明人: Xiaoqing Han , Alan Whitehead , Subharekha Raghavan , Timothy A. Cernak , Spencer Dreher , Jonathan Groeper , Jian Guo , Yong Zhang
- 申请人: Xiaoqing HAN , Alan WHITEHEAD , Subharekha RAGHAVAN , Timothy A. CERNAK , Spencer DREHER , Jonathan GROEPER , Jian GUO , Yong ZHANG , MERCK SHARP & DOHME CORP.
- 申请人地址: US NJ Rahway
- 专利权人: Merck Sharp & Dohme Corp.
- 当前专利权人: Merck Sharp & Dohme Corp.
- 当前专利权人地址: US NJ Rahway
- 国际申请: PCT/US14/68689 WO 20141205
- 主分类号: C07D519/00
- IPC分类号: C07D519/00 ; A61K45/06 ; A61K31/519
摘要:
A compound of Formula I or a pharmaceutically acceptable salt thereof, are capable of modulating the body's production of cyclic guanosine monophosphate (“cGMP”) and are generally suitable for the therapy and prophylaxis of diseases which are associated with a disturbed cGMP balance. The invention furthermore relates to processes for preparing compounds of Formula I, or a pharmaceutically acceptable salt thereof, for their use in the therapy and prophylaxis of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and to pharmaceutical preparations which comprise compounds of Formula I or a pharmaceutically acceptable salt thereof.
公开/授权文献
- US09783552B2 Soluble guanylate cyclase activators 公开/授权日:2017-10-10
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