- 专利标题: PSCA: PROSTATE STEM CELL ANTIGEN AND USES THEREOF
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申请号: US15181019申请日: 2016-06-13
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公开(公告)号: US20160347855A1公开(公告)日: 2016-12-01
- 发明人: Robert E. Reiter , Owen N. Witte , Douglas C. Saffran , Aya Jakobovits
- 申请人: The Regents of the University of California , Agensys, Inc.
- 主分类号: C07K16/30
- IPC分类号: C07K16/30 ; G01N33/577 ; A61K51/10 ; A61K45/06 ; A61K31/704 ; G01N33/574 ; A61K39/395
摘要:
The invention provides a novel prostate cell-surface antigen, designated Prostate Stem Cell Antigen (PSCA), which is widely over-expressed across all stages of prostate cancer, including high grade prostatic intraepithelial neoplasia (PIN), androgen-dependent and androgen-independent prostate tumors.