The present disclosure discloses a system and method for interface call, relating to the enterprise management technology field. The system includes: an interface management component which is configured to generate a description file and a call process indication of an interface according to an interface modification requirement of a user, and deploy the description file and the call process indication to an interface execution component, wherein the description file includes configuration replacement information of the interface; and the interface execution component, which is configured to configure the interface according to the description file, and call the interface according to the call process indication. The technical solution of the present disclosure enables data interaction of an interface between different systems, thereby improving work efficiency. In addition, the system of the present disclosure is simple in structure and the method is easy to implement, so a input cost of the system in enterprises can be saved.