发明申请
US20160376302A1 N-ALKYL 2-(DISUBSTITUTED)ALKYNYLADENOSINE-5-URONAMIDES AS A2A AGONISTS
有权
N-烷基2-(取代的)亚烷基腺嘌呤-5-尿苷作为A2A激动剂
- 专利标题: N-ALKYL 2-(DISUBSTITUTED)ALKYNYLADENOSINE-5-URONAMIDES AS A2A AGONISTS
- 专利标题(中): N-烷基2-(取代的)亚烷基腺嘌呤-5-尿苷作为A2A激动剂
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申请号: US14752861申请日: 2015-06-27
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公开(公告)号: US20160376302A1公开(公告)日: 2016-12-29
- 发明人: Robert D. Thompson , Anthony Beauglehole , Guoquan Wang
- 申请人: Robert D. Thompson , Anthony Beauglehole , Guoquan Wang
- 主分类号: C07H19/16
- IPC分类号: C07H19/16 ; A61K49/00
摘要:
The present invention provides N-alkyl 2-(disubstituted)alkynyladenosine-5′-uronamides and derivatives thereof and pharmaceutical compositions containing the same that are selective agonists of A2A adenosine receptors (ARs). These compounds and compositions are useful as pharmaceutical agents.
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