Invention Application
US20170008972A1 ANTIBODIES BINDING TO AN INTRACELLULAR PRL-1 OR PRL-3 POLYPEPTIDE
审中-公开
抗体与细胞内PRL-1或PRL-3多肽的结合
- Patent Title: ANTIBODIES BINDING TO AN INTRACELLULAR PRL-1 OR PRL-3 POLYPEPTIDE
- Patent Title (中): 抗体与细胞内PRL-1或PRL-3多肽的结合
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Application No.: US15073231Application Date: 2016-03-17
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Publication No.: US20170008972A1Publication Date: 2017-01-12
- Inventor: Qi Zeng
- Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
- Applicant Address: SG Singapore
- Assignee: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
- Current Assignee: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
- Current Assignee Address: SG Singapore
- Main IPC: C07K16/40
- IPC: C07K16/40

Abstract:
We provide an antibody capable of binding to an intracellular PRL-I or PRL-3 polypeptide, in which the antibody is capable of binding to an epitope bound by antibody 269, antibody 223 or antibody 318. Such anti-PRL antibodies may be capable of binding to intracellular PRL-I or PRL-3. They may be suitable for use as therapies against cancer or metastasis thereof, or in clinical diagnosis to identify PRL-3 or PRL-1 positive patients.
Public/Granted literature
- US10174126B2 Antibodies binding to an intracellular PRL-1 or PRL-3 polypeptide Public/Granted day:2019-01-08
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