A process of manufacturing antimicrobial fabrics includes drying Rheum rhabarbarum, Sophora flavescens var. Flavescens, Forsythia suspensa, Coptis chinensis Franch, Rehmannia glutinosa, Anemarrhena asphodeloides, and Scutellaria lateriflora at 50° C. for about 6 to 12 hours, and grinding same to nanoscale powders; adding the nanoscale powders to a solution containing 95% by volume of ethanol, heating the solution at 50° C., and extracting the ethanol; adding water to the container after extracting for two hours, thereby obtaining a solution containing antimicrobial herbal medicinal components; adding about 1 to 3 wt % of Sodium dodecyl sulfate to the solution containing antimicrobial herbal medicinal components for emulsification; adding about 5 wt % of acrylic resin to the emulsified solution to form Liposomes containing the nano powder; adding the Liposomes to foam resin to form a mixture; and applying the mixture to fabrics to manufacture antimicrobial fabrics containing herbal medicinal components.