Invention Application
- Patent Title: METHODS FOR THE SYNTHESIS OF FUNCTIONALIZED NUCLEIC ACIDS
- Patent Title (中): 用于合成功能性核酸的方法
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Application No.: US15222910Application Date: 2016-07-28
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Publication No.: US20170029457A1Publication Date: 2017-02-02
- Inventor: Gregory L. Verdine , Meena , Naoki Iwamoto , David Charles Donnell Butler
- Applicant: WAVE LIFE SCIENCES LTD.
- Main IPC: C07H21/04
- IPC: C07H21/04

Abstract:
Described herein are methods for the synthesis of derivatives of thiosulfonate reagents. Said reagents have utility for the synthesis of phosphorothiotriesters from H-phosphonates in a stereospecific fashion.
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