Invention Application
- Patent Title: TRIAZOLE AGONISTS OF THE APJ RECEPTOR
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Application No.: US15298434Application Date: 2016-10-20
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Publication No.: US20170044131A1Publication Date: 2017-02-16
- Inventor: Ning CHEN , Xiaoqi CHEN , Yinhong CHEN , Alan C. CHENG , Richard V. CONNORS , Jeffrey DEIGNAN , Paul John DRANSFIELD , Xiaohui DU , Zice FU , Julie Anne HEATH , Daniel B. HORNE , Jonathan HOUZE , Matthew R. KALLER , Aarif Yusuf KHAKOO , David John KOPECKY , Su-Jen LAI , Zhihua MA , Lawrence R. MCGEE , Julio C. MEDINA , Jeffrey T. MIHALIC , Nobuko NISHIMURA , Steven H. OLSON , Vatee PATTAROPONG , Gayathri SWAMINATH , Xiaodong WANG , Kevin YANG , Wen-Chen YEH , Mikkel V. DEBENEDETTO , Robert P. FARRELL , Simon J. HEDLEY , Ted C. JUDD , Frank KAYSER
- Applicant: AMGEN INC.
- Main IPC: C07D401/04
- IPC: C07D401/04 ; A61K45/06 ; C07D401/14 ; A61K31/506 ; C07D417/14 ; A61K31/444 ; A61K31/497 ; A61K31/513 ; C07D471/04 ; A61K31/4439 ; C07D413/14
Abstract:
Compounds of Formula I and Formula II, pharmaceutically acceptable salt thereof, stereoisomers of any of the foregoing, or mixtures thereof are agonists of the APJ Receptor and have use in treating cardiovascular and other conditions. Compounds of Formula I and Formula II have the following structures: where the definitions of the variables are provided herein.
Public/Granted literature
- US09751864B2 Methods for preparing triazole agonists of the APJ receptor Public/Granted day:2017-09-05
Information query
