发明申请
- 专利标题： EXTENDED PRODUCTION OF NITRIC OXIDE FROM A MICROENCAPSULATED NITRITE SALT AND AN AQUEOUS ACIDIFIED GEL
- 专利标题（中）： 从微型硝酸盐和水性酸性凝胶中扩大生产氧化亚氮
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申请号： US15268560申请日： 2016-09-17
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公开(公告)号： US20170065630A1公开(公告)日： 2017-03-09
- 发明人: Cheng-Shing Chen , Ferid Murad , Kenneth A. Smith , WIlliam A. Seitz , William J. Merrell , Alexandru T. Balaban
- 申请人： NIOXX LLC
- 主分类号： A61K33/00
- IPC分类号： A61K33/00 ; A61K9/70 ; A61K9/06 ; A61K31/194 ; A61K31/375 ; A61K9/50 ; C01B21/24 ; A61K33/22
摘要：
Methods and compositions are provided for generating and applying long-lasting therapeutic nitric oxide (NO) gas from the reaction of a least one microencapsulated nitrite salt and an activating volume of an aqueous acidified gel that has sufficient acidity to convert the nitrite salt to a nitric oxide (NO) and further provides a reducing property that retains the NO in bioactive form
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