Invention Application
- Patent Title: INDOLINONE COMPOUNDS AND USES THEREOF
-
Application No.: US15357876Application Date: 2016-11-21
-
Publication No.: US20170066720A1Publication Date: 2017-03-09
- Inventor: Jean-Michel Vernier
- Applicant: Oncternal Therapeutics, Inc.
- Main IPC: C07D209/38
- IPC: C07D209/38 ; C07D401/06 ; C07D403/10
Abstract:
Indolinone derivative compounds that act as EWS-FLI1 transcription factor inhibitors are provided. Also provided are pharmaceutical compositions of the indolinone derivatives, methods of synthesizing the same, methods of treating using same, and assays for identifying the inhibitors of EWS-FLI1 oncoprotein.
Public/Granted literature
- US09987251B2 Indolinone compounds and uses thereof Public/Granted day:2018-06-05
Information query
