发明申请
US20170071964A1 METHODS FOR TREATING ARENAVIRIDAE AND CORONAVIRIDAE VIRUS INFECTIONS
审中-公开
治疗ARENAVIRIDAE和CORONAVIRIDAV病毒感染的方法
- 专利标题： METHODS FOR TREATING ARENAVIRIDAE AND CORONAVIRIDAE VIRUS INFECTIONS
- 专利标题（中）： 治疗ARENAVIRIDAE和CORONAVIRIDAV病毒感染的方法
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申请号： US15267433申请日： 2016-09-16
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公开(公告)号： US20170071964A1公开(公告)日： 2017-03-16
- 发明人: Michael O' Neil Hanrahan Clarke , Joy Yang Feng , Robert Jordan , Richard L. Mackman , Adrian S. Ray , Dustin Siegel
- 申请人： Gilead Sciences, Inc.
- 主分类号： A61K31/706
- IPC分类号： A61K31/706 ; A61K45/06
摘要：
Provided are methods for treating Arenaviridae and Coronaviridae virus infections by administering nucleosides and prodrugs thereof, of Formula I: wherein the 1′ position of the nucleoside sugar is substituted. The compounds, compositions, and methods provided are particularly useful for the treatment of Lassa virus and Junin virus infections.