Invention Application
- Patent Title: Novel Methods for Freeze-drying and Rehydrating Biologics
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Application No.: US15311093Application Date: 2015-05-13
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Publication No.: US20170087230A1Publication Date: 2017-03-30
- Inventor: Noel Yves Henri Jean Genin , Jean-Christophe Audonnet , Didier Roy , Edouard Seche , Patrick Gervais , Samira Khaldi-Plassart , Romain Useo , Joelle DeConinck
- Applicant: MERIAL INC. , VITAMFERO S.A , L'UNIVERSITE DE BOURGOGNE , L'Institut National Superieur des Sciences Agronomiques de L'Alimentation et de L'Environmen
- Applicant Address: US GA DULUTH FR Angers FR Dijon Cedex FR BP 87999
- Assignee: MERIAL INC.,VITAMFERO S.A,L'Universite De Bourgogne,L'Institut National Superieur des Sciences Agronom iques de L'Alimentation et de L'Environment
- Current Assignee: MERIAL INC.,VITAMFERO S.A,L'Universite De Bourgogne,L'Institut National Superieur des Sciences Agronom iques de L'Alimentation et de L'Environment
- Current Assignee Address: US GA DULUTH FR Angers FR Dijon Cedex FR BP 87999
- Priority: EP14168327.6 20140514
- International Application: PCT/US15/30588 WO 20150513
- Main IPC: A61K39/002
- IPC: A61K39/002 ; A61K9/19 ; A01N1/02
Abstract:
The present invention relates generally to the fields of immunology and vaccine technology. More specifically, the present invention relates to methods for freeze-drying biological preparations, including peptides, antigens, antibodies, and especially, cells. Importantly, the disclosed methods preserve the viability, infectivity and immunogenicity of cells from the Apicomplexa phylum, the Sarcocystidae family, and in particular, cells from the Toxoplasma genus.
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