Invention Application
- Patent Title: PRMT5 INHIBITORS AND USES THEREOF
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Application No.: US15150759Application Date: 2016-05-10
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Publication No.: US20170088541A1Publication Date: 2017-03-30
- Inventor: Kenneth W. Duncan , Richard Chesworth , Michael John Munchhof
- Applicant: Epizyme, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Epizyme, Inc.
- Current Assignee: Epizyme, Inc.
- Current Assignee Address: US MA Cambridge
- Main IPC: C07D401/06
- IPC: C07D401/06 ; C07D413/06 ; C07D401/14
Abstract:
Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity. Methods of using the compounds for treating PRMT5-mediated disorders are also described.
Public/Granted literature
- US10150758B2 PRMT5 inhibitors and uses thereof Public/Granted day:2018-12-11
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