- 专利标题： TRKA KINASE INHIBITORS, COMPOSITIONS AND METHODS THEREOF
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申请号： US15128793申请日： 2015-03-23
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公开(公告)号： US20170107204A1公开(公告)日： 2017-04-20
- 发明人: Helen Mitchell , Harold B. Wood , Chun Sing Li , Qinghua Mao , Zhiqi Qi
- 申请人： Helen MITCHELL , Harold WOOD , Chun Sing LI , Qinghua MAO , Zhiqi QI , Merck Sharp & Dohme Corp.
- 申请人地址： US NJ Rahway
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： US NJ Rahway
- 优先权： CNPCT/CN2014/074143 20140326
- 国际申请： PCT/US15/21952 WO 20150323
- 主分类号： C07D403/12
- IPC分类号： C07D403/12 ; C07D401/12 ; C07D487/04 ; C07D471/04 ; C07D403/14
摘要：
The present invention is directed to a bicyclic heteroaryl benzamide compounds of formula (I) which are tropomyosin-related kinase (Trk) family protein kinase inhibitors, and hence are useful in the treatment of pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder associated with abnormal activities of nerve growth factor (NGF) receptor TrkA.
公开/授权文献
- US09862707B2 TrkA kinase inhibitors, compositions and methods thereof 公开/授权日：2018-01-09
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