Invention Application
- Patent Title: IMIDAZOLE COMPOUND AND LIPOSOME CONTAINING SAME
-
Application No.: US15406050Application Date: 2017-01-13
-
Publication No.: US20170119667A1Publication Date: 2017-05-04
- Inventor: Toyohisa OYA , Ayumi ISHIYAMA , Naoyuki NISHIKAWA
- Applicant: FUJIFILM Corporation
- Applicant Address: JP Tokyo
- Assignee: FUJIFILM Corporation
- Current Assignee: FUJIFILM Corporation
- Current Assignee Address: JP Tokyo
- Priority: JP2014-146810 20140717
- Main IPC: A61K9/127
- IPC: A61K9/127 ; A61K47/22 ; C07D233/64

Abstract:
Provided are a novel imidazole compound which has a high stability of the compound itself; and a novel imidazole compound which is useful as a membrane-constituting lipid of liposomes. Disclosed are a compound represented by the following General Formula (1), and a liposome containing the same compound. In the formula, Z is an imidazolyl group which may be substituted, L1 is an alkylene group having 1 to 4 carbon atoms which may be substituted, X is an oxygen atom or a nitrogen-containing substituent, n is an integer of 2 to 4, m is an integer of 1 to 20, L2 is a divalent linking group having 1 to 6 carbon atoms, Y is a nitrogen-containing group, R1 and R2 are a hydrogen group or an alkyl group having 1 to 6 carbon atoms, R3 is a hydrogen atom or a substituent, and R4 and R5 are an alkyl group having 1 to 40 carbon atoms.
Public/Granted literature
- US09795566B2 Imidazole compound and liposome containing same Public/Granted day:2017-10-24
Information query