发明申请
- 专利标题： Enzymes Functional Probes
-
申请号： US15039350申请日： 2014-11-28
-
公开(公告)号： US20170122958A1公开(公告)日： 2017-05-04
- 发明人: Enrique Lin Shiao , Matthias Gerard Jacky Baud , Alessio Ciulli , Kwok-Ho Chan , Michael Zengerle
- 申请人： University of Dundee , Cambridge Enterprise Limited
- 优先权： GB1320994.5 20131128; GB1401001.1 20140121
- 国际申请： PCT/GB2014/053549 WO 20141128
- 主分类号： G01N33/68
- IPC分类号： G01N33/68 ; C07D487/04 ; C12N15/10
摘要：
A method of selectively inhibiting a bromodomain in the presence of other bromodomains comprising introducing a functionally silent mutation into the bromodomain in the presence of other wild type bromodomains and selectively inhibiting the mutated bromodomain.
信息查询
IPC分类:
