- 专利标题： CHIMERIC ANTIGEN RECEPTOR AND METHODS OF USE THEREOF
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申请号： US15419729申请日： 2017-01-30
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公开(公告)号： US20170143765A1公开(公告)日： 2017-05-25
- 发明人: Chia-Yung Wu , James Onuffer , Wendell A. Lim
- 申请人： The Regents of the University of California
- 主分类号： A61K35/17
- IPC分类号： A61K35/17 ; C07K16/18 ; C07K14/725 ; C12N5/0783 ; C07K16/28 ; C07K14/705
摘要：
The present disclosure provides a heterodimeric, conditionally active chimeric antigen receptor (CAR), and a nucleic acid comprising a nucleotide sequence encoding the CAR. The present disclosure provides cells genetically modified to produce the CAR. A CAR of the present disclosure can be used in various methods, which are also provided.
公开/授权文献
- US09821012B2 Chimeric antigen receptor and methods of use thereof 公开/授权日：2017-11-21
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