A method of printing a part in an electrophotographic additive manufacturing system includes printing a part and associated support structure in a layer by layer manner, and providing a chamber in which printing is performed. The chamber is supported by a movable platform and the chamber is positioned about a movable platen. The movable platen is supported by the movable build platform. The movable platen is movable within the chamber on the movable build platform. An electrophotography-based additive manufacturing system for printing a three-dimensional part includes a transfer medium configured to receive and transfer imaged layers of a three-dimensional part, and a support from one or more imaging engines. The system includes a heater configured to heat the imaged layers on the transfer medium to at least a fusion temperature, and a layer transfusion assembly configured to transfuse the imaged layers to the build platen or a previously printed layer.