- 专利标题： BETULINIC ACID DERIVATIVES WITH HIV MATURATION INHIBITORY ACTIVITY
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申请号： US15313139申请日： 2015-06-17
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公开(公告)号： US20170204133A1公开(公告)日： 2017-07-20
- 发明人: Alicia REGUEIRO-REN , Animesh GOSWAMI , Zhiwei GUO , Thomas P. TULLY , Jacob SWIDORSKI , Zheng LIU , Nicholas A. MEANWELL
- 申请人： ViiV Healthcare UK (No.5) Limited
- 国际申请： PCT/US2015/036191 WO 20150617
- 主分类号： C07J63/00
- IPC分类号： C07J63/00 ; C07J71/00
摘要：
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, betulinic acid derivaties that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I, II and III: These compounds are useful for the treatment of HIV and AIDS.
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