A touch display substrate, a touch display panel, a touch display screen and an electronic device are disclosed. The touch display substrate includes a base substrate and a wire grid polarizer (WGP) disposed on one side of the base substrate. The WGP includes a plurality of metal wires disposed in parallel; and the metal wires are configured for connecting with the touch integrated circuit (IC). The thickness of the touch display substrate is reduced, and the difficulty of coordinating the touch IC and the display IC is reduced.