Invention Application
- Patent Title: INDOLINE SULFONAMIDE INHIBITORS OF DAPE AND NDM-1 AND USE OF THE SAME
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Application No.: US15501489Application Date: 2015-08-12
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Publication No.: US20170226090A1Publication Date: 2017-08-10
- Inventor: Daniel Paul Becker , Richard C. Holz , Tahirah K. Heath , Cory Reidl , Anna Starus , Walter Fast
- Applicant: LOYOLA UNIVERSITY OF CHICAGO , MARQUETTE UNIVERSITY , Board of Regents, The University of Texas System
- International Application: PCT/US15/44915 WO 20150812
- Main IPC: C07D403/12
- IPC: C07D403/12 ; C07D401/12 ; C07D209/10
Abstract:
Indoline sulfonamide compounds that can inhibit DapE and/or bacterial metallo-β-lactamases (MBLs), such as NDM-1, are disclosed. Also disclosed are methods of treating an individual suffering from a bacterial infection using the indoline sulfonamide compounds disclosed herein.
Public/Granted literature
- US10385040B2 Indoline sulfonamide inhibitors of DapE and NDM-1 and use of the same Public/Granted day:2019-08-20
Information query
