- 专利标题： MICELLE CONTAINING EPIRUBICIN-COMPLEXED BLOCK COPOLYMER AND ANTI-CANCER AGENT, AND PHARMACEUTICAL COMPOSITION CONTAINING SAID MICELLE APPLICABLE TO TREATMENT OF CANCER, RESISTANT CANCER OR METASTATIC CANCER
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申请号： US15503370申请日： 2015-08-11
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公开(公告)号： US20170258922A1公开(公告)日： 2017-09-14
- 发明人: Hiroaki Kinoh , Kazunori Kataoka , Horacio Cabral , Yutaka Miura , Shigeto Fukushima , Nobuhiro Nishiyama , Tsukasa Chida
- 申请人： The University of Tokyo , Tokyo Institute of Technology
- 优先权： JP2014-163989 20140811
- 国际申请： PCT/JP2015/072797 WO 20150811
- 主分类号： A61K9/127
- IPC分类号： A61K9/127 ; A61K31/553 ; A61K31/4545 ; A61K31/475 ; A61K31/704 ; A61K31/4402 ; A61K47/48 ; C08L77/04
摘要：
The problem addressed by the present invention is to develop a pharmaceutical having therapeutic efficacy against epirubicin-resistant tumors. The present invention provides a micelle having an anti-cancer agent disposed inside the core of the micelle formed by an epirubicin-conjugated copolymer.
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