Invention Application
- Patent Title: BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS
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Application No.: US15601423Application Date: 2017-05-22
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Publication No.: US20170260207A1Publication Date: 2017-09-14
- Inventor: Robert John AVERSA , Paul Andrew BARSANTI , Matthew T. BURGER , Michael Patrick DILLON , Alan DIPESA , Cheng HU , Yan LOU , Gisele A. NISHIGUCHI , Yue PAN , Valery Rostislavovich POLYAKOV , Savithri RAMURTHY , Alice C. RICO , Lina Quattrocchio SETTI , Aaron SMITH , Sharadha SUBRAMANIAN , Benjamin R. TAFT , Huw Roland TANNER , Lifeng WAN , Naeem YUSUFF
- Applicant: NOVARTIS AG
- Main IPC: C07D513/04
- IPC: C07D513/04 ; A61K31/5377 ; C07D213/74 ; C07D237/22 ; C07D213/84 ; C07D213/81 ; C07D213/75 ; C07D401/14 ; C07D405/14 ; C07D413/12 ; C07D413/14 ; C07D491/08 ; A61K31/444 ; C07D241/20 ; C07D401/04 ; C07D237/24 ; C07D237/20 ; A61K31/501 ; C07D239/48 ; C07D403/04 ; C07D487/04 ; C07D471/04 ; C07D263/58 ; C07D495/04 ; C07D491/04 ; C07D409/14 ; C07D413/04 ; C07B59/00 ; C07D401/12

Abstract:
The present invention provides compounds of Formula (I) as described herein, and salts thereof, and therapeutic uses of these compounds for treatment of disorders associated with Raf kinase activity. The invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds and a therapeutic co-agent.
Public/Granted literature
- US10245267B2 Biaryl amide compounds as kinase inhibitors Public/Granted day:2019-04-02
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