Invention Application
- Patent Title: TUBULYSIN COMPOUNDS, METHODS OF MAKING AND USE
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Application No.: US15602156Application Date: 2017-05-23
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Publication No.: US20170260232A1Publication Date: 2017-09-14
- Inventor: Qiang CONG , Heng CHENG , Sanjeev GANGWAR
- Applicant: Bristol-Myers Squibb Company
- Main IPC: C07K5/117
- IPC: C07K5/117 ; C07K5/06 ; C07K5/078 ; C07K5/10 ; C07K7/06 ; A61K38/07 ; A61K38/05
Abstract:
Tubulysin compounds of the formula (I) where R1, R2 R3a, R3b, R4, R5, W, and n are as defined herein, are anti-mitotic agents that can be used in the treatment of cancer, especially when conjugated to a targeting moiety.
Information query
