A chain drive for an internal combustion engine comprises a driving sprocket and at least one driven sprocket, a drive chain coupling the sprockets to each other, and at least one guide rail and/or one tensioning rail for guiding and/or tensioning the drive chain. At least the guide rail and/or the tensioning rail comprises at least two slide elements, arranged at a non-guided distance from one another for contacting the drive chain, such that at least two slide elements are arranged in at least one span of the chain drive. In at least one span, the ratio of guided chain length to non-guided chain length is smaller than 1. Such a chain drive is to be improved with respect to its vibration characteristics. To this end, the sum of the two non-guided lengths of the drive chain between a slide element and the respective nearest sprocket is, in at least one span, which is in contact with a guide rail and/or a tensioning rail with at least two slide elements arranged at a non-guided distance from one another, smaller than 0.5 times the total length of the respective span.