Some embodiments of the present disclosure provide a content integration system. The content integration system is configured to retrieve a source digital content, retrieve a target digital content, identify a region within the target digital content for placing or integrating the source digital content, and place or integrate the target digital content onto the identified region of the source digital content. The content integration system can be configured to place the source digital content into the target digital content in an aesthetically-pleasing, unobtrusive, engaging, and/or otherwise favorable manner. The content integration system can be particularly useful for advertisements, enhanced expression, entertainment, information, or communication.