- 专利标题： APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
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申请号： US14961748申请日： 2015-12-07
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公开(公告)号： US20170296531A9公开(公告)日： 2017-10-19
- 发明人: Le Wang , George Doherty , Xilu Wang , Zhi-Fu Tao , Milan Bruncko , Aaron R. Kunzer , Michael D. Wendt , Xiaohong Song , Robin Frey , Todd M. Hansen , Gerard M. Sullivan , Andrew Judd , Andrew J. Souers
- 申请人： AbbVie Inc.
- 主分类号： A61K31/4725
- IPC分类号： A61K31/4725 ; C07D493/08 ; C07D487/04 ; C07D417/14 ; C07D401/04 ; A61K31/541 ; A61K31/5377 ; A61K31/5025 ; A61K31/4985 ; C07D513/04 ; C07D471/04
摘要：
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-xL protein.
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