An engine coolant monitoring system for a machine is disclosed. The engine coolant monitoring system may have a test device configured to test a fluid sample of an engine coolant. The engine coolant monitoring system may also have a database configured to store a test result generated by the test device, the test result including a plurality of characteristics of the fluid sample. In addition, the engine coolant monitoring system may have a controller. The controller may be configured to access a rule-set associated with the engine coolant from the database, the rule-set having criteria associated with the characteristics. The controller may also be configured to label the engine coolant as normal when the characteristics of the fluid sample satisfy the criteria and label the engine coolant as abnormal when the characteristics do not satisfy at least one criterion included in the rule-set.