A portable irradiation device is disclosed including: a hollow squeezing part operable to squeeze air therein out; a sucker having a first end opening portion and a second end opening portion, the first end opening portion being hermetically connected with the squeezing part, the second end opening portion being attachable to a human body by means of a difference in air pressure between inside and outside the sucker; and a blue light irradiation unit located in a space surrounded by the squeezing part, the sucker, or the squeezing part and the sucker. Also disclosed is a method for manufacturing a portable irradiation device.