Provided herein are herbicidal compositions containing of (a) fluroxypyr or an agriculturally acceptable ester or salt thereof and (b) an ALS-inhibiting herbicide, wherein the ALS-inhibiting herbicide is diclosulam, cloransulam, chlorimuron, or thifensulfuron, or an agriculturally acceptable ester or salt thereof. The compositions provide synergistic weed control of undesirable vegetation in areas including, but not limited to, soybean, cotton, corn, sorghum, sunflower, sugarcane, sugar beets, alfalfa, cereals (including but not limited to wheat, barley, rice and oats), non-crop, fallow-bed, perennial crop, fruiting crop, or plantation crop areas.