发明申请
- 专利标题: SITE-SPECIFIC CONJUGATION THROUGH GLYCOPROTEINS LINKAGE AND METHOD THEREOF
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申请号: US15541020申请日: 2015-12-31
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公开(公告)号: US20170369525A1公开(公告)日: 2017-12-28
- 发明人: Chao-Pin Lee , Cheng-Chou Yu , Chi-Huey Wong , Chuan-Lung Hsu , Chun-Chung Lee , Shih-Hsien Chuang , Ta-Tung Yuan , Yi-Jen Chen , Yu-Chin Nieh
- 申请人: Development Center for Biotechnology , DCB-USA LLC
- 申请人地址: TW New Taipei City US DE Wilmington
- 专利权人: Development Center for Biotechnology,DCB-USA LLC
- 当前专利权人: Development Center for Biotechnology,DCB-USA LLC
- 当前专利权人地址: TW New Taipei City US DE Wilmington
- 国际申请: PCT/US2015/068300 WO 20151231
- 主分类号: C07K1/107
- IPC分类号: C07K1/107 ; C07K1/08 ; A61K39/395 ; C07K16/18 ; A61K47/68
摘要:
A method for specific linkage to a glycoprotein includes obtaining a glycoprotein having a monoglycan or diglycan attached thereto; producing a reactive functional group on a sugar unit on the glycoprotein; and coupling a linker or a payload to the reactive functional group on the glycoprotein.
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