发明申请
- 专利标题： IMIDAZOPYRAZINE ANALOGS WITH 3-TERTIARY CARBON SUBSTITUTIONS AS BTK INHIBITORS
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申请号： US15538957申请日： 2015-12-17
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公开(公告)号： US20180009828A1公开(公告)日： 2018-01-11
- 发明人: JIAN LIU , JOSEPH A. KOZLOWSKI , XIAOLEI GAO , DEODIAL GUY GUIADEEN , SHILAN LIU , DAHAI WANG
- 申请人： JIAN LIU , JOSEPH A. KOZLOWSKI , XIAOLEI GAO , DEODIAL GUY GUIADEEN , SHILAN LIU , DAHAI WANG
- 申请人地址： US NJ RAHWAY
- 专利权人： MERCK SHARP & DOHME CORP.
- 当前专利权人： MERCK SHARP & DOHME CORP.
- 当前专利权人地址： US NJ RAHWAY
- 优先权： CNPCT/CN2014/095767 20141231
- 国际申请： PCT/US15/66225 WO 20151217
- 主分类号： C07D519/00
- IPC分类号： C07D519/00 ; A61K31/4985
摘要：
The present invention provides Bruton's Tyrosine Kinase (Btk) inhibitor compounds according to Formula (I), or pharmaceutically acceptable salts thereof, Formula (I) or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of Btk inhibitor compounds of Formula I in the treatment of Btk mediated disorders.
公开/授权文献
- US10040805B2 Substituted imidazo[1,5-a]pyrazines as Btk inhibitors 公开/授权日：2018-08-07