发明申请
- 专利标题： Factor IXa Inhibitors
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申请号： US15534029申请日： 2015-12-07
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公开(公告)号： US20180030036A1公开(公告)日： 2018-02-01
- 发明人: Ting Zhang , Yi-Heng Chen , Liangqin Guo , Alan Hruza , Tianying Jian , Bing Li , Dongfang Meng , Dann L. Parker , Edward C. Sherer , Harold B. Wood , Isao Sakurada
- 申请人： Ting ZHANG , Yi-Heng CHEN , Liangqin GUO , Alan HARUZA , Tianying JIAN , Bing LI , Dongfang MENG , Dann L. PARKER, JR. , Edward C. SHERER , Harold B. WOOD , Isao SAKURADA , MERCK SHARP & DOHME CORP. , MOCHIDA PHARMACEUTICAL CO., LTD
- 申请人地址： US NJ Rahway JP Tokyo
- 专利权人： MERCK SHARP & DOHME CORP.,MOCHIDA PHARMACEUTICAL CO., LTD
- 当前专利权人： MERCK SHARP & DOHME CORP.,MOCHIDA PHARMACEUTICAL CO., LTD
- 当前专利权人地址： US NJ Rahway JP Tokyo
- 国际申请： PCT/US15/64176 WO 20151207
- 主分类号： C07D403/12
- IPC分类号： C07D403/12 ; C07D401/14 ; C07D401/12 ; C07D471/04
摘要：
The present invention provides a compound of Formula I, and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing unstable angina, refractory angina, myocardial infarction, transient ischemic attacks, atrial fibrillation, thrombotic stroke, embolic stroke, deep vein thrombosis, disseminated intravascular coagulation, ocular build up of fibrin, and reocclusion or restenosis of recanalized vessels. The compounds are selective Factor IXa inhibitors.
公开/授权文献
- US10189819B2 Factor IXa inhibitors 公开/授权日：2019-01-29
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