- 专利标题： IL-10-PRODUCING CD4+ T CELLS AND USES THEREOF
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申请号： US15557263申请日： 2016-03-11
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公开(公告)号： US20180050092A1公开(公告)日： 2018-02-22
- 发明人: Silvia Adriana GREGORI , Maria Grazia RONCAROLO
- 申请人： FONDAZIONE TELETHON , OSPEDALE SAN RAFFAELE SRL , FONDAZIONE CENTRO SAN RAFFAELE
- 申请人地址： IT Roma IT Milano IT Milano
- 专利权人： FONDAZIONE TELETHON,OSPEDALE SAN RAFFAELE SRL,FONDAZIONE CENTRO SAN RAFFAELE
- 当前专利权人： FONDAZIONE TELETHON,OSPEDALE SAN RAFFAELE SRL,FONDAZIONE CENTRO SAN RAFFAELE
- 当前专利权人地址： IT Roma IT Milano IT Milano
- 国际申请： PCT/EP2016/055353 WO 20160311
- 主分类号： A61K38/20
- IPC分类号： A61K38/20 ; A61K35/17 ; G01N33/574
摘要：
The present invention relates to a CD4+ T cell that produces high levels of IL-10 for use in the treatment and/or prevention of a tumor that expresses CD13, HLA-class I and CD54 and/or for use in inducing Graft versus tumour (GvT). The present invention relates also to a composition comprising said cell and to a method to select a subject to be treated with said cell.
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