A dual-mode, hand-held, digital probe, designed to rapidly localize tissues of interest through gamma detection, and provide high-resolution, real-time images of the suspect area by sensing beta radiation is presented. A position-sensitive solid-state photomultiplier is optically bonded with a hybrid scintillator including a thin Crystalline Microcolumnar Structure (CMS) CsI:T1 scintillator, vapor-deposited directly onto a monolithic (polycrystalline) LYSO scintillator.