An automatic medicine retrieving device includes a medicine tray, a medicine box, and a driving mechanism. The medicine tray includes a bearing plate defining an exit port and a medicine separating member rotatably positioned on the bearing plate. The medicine separating member has medicine separating areas and a positioning area. Medications in the form of pills are positioned on the bearing plate and received in the medicine separating areas. The medicine box is opposite to the exit port. The driving mechanism drives the medicine separating member to rotate from being opposite to the exit port, bringing the medicine separating area to a position opposite to the exit port. A pill in the medicine separating area then passes through the exit port to fall into an accepting mechanism.