A wireless device and a radio frequency channel calibration method, where the wireless device includes a first radio frequency circuit and a second radio frequency circuit that operate on a same frequency band, and a processor. The first radio frequency circuit is configured to send a calibration signal using a calibration antenna. The second radio frequency circuit is configured to receive the calibration signal using each of at least two to-be-calibrated antennas. The second radio frequency circuit corresponds to at least two radio frequency channels, the at least two radio frequency channels respectively correspond to the at least two to-be-calibrated antennas. The processor is configured to determine a device phase difference of each of the at least two radio frequency channels, and calibrate a corresponding radio frequency channel using the device phase difference of each of the at least two radio frequency channels.