![CYCLIC ETHER DERIVATIVES OF PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYAMIDE](/docs/US/2018-05-17/US20180134720A1/abs.jpg.600x600.jpg)
- 专利标题： CYCLIC ETHER DERIVATIVES OF PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYAMIDE
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申请号： US15865695申请日： 2018-01-09
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公开(公告)号： US20180134720A1公开(公告)日： 2018-05-17
- 发明人: Christoph HOENKE , Barbara BERTANI , Marco FERRARA , Giacomo FOSSATI , Sara FRATTINI , Riccardo GIOVANNINI , Scott HOBSON
- 申请人： Boehringer Ingelheim International GmbH
- 优先权： EP15189600.8 20151013
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/519
![CYCLIC ETHER DERIVATIVES OF PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYAMIDE](/abs-image/US/2018/05/17/US20180134720A1/abs.jpg.150x150.jpg)
摘要：
The invention relates to Spirocyclic ether derivatives of pyrazolo[1,5-a]pyrimidine-3-carboxyamide of general formula (I) which are inhibitors of phosphodiesterase 2, useful in treating central nervous system diseases and other diseases. In addition, the invention relates to processes for preparing pharmaceutical compositions as well as processes for manufacture the compounds according to the invention.
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