A system, computer readable medium, and method are provided for calibrating a wireless transmitter. A transceiver that includes a radio frequency transmitter, a measurement receiver, and a local oscillator unit may be calibrated by adjusting the duty cycle of the radio frequency signals generated by the local oscillator unit. The method for calibrating the wireless transmitter includes the steps of collecting measurement data corresponding to a number of pre-defined duty ratio correction factors, calculating estimated optimum duty ratio correction factors based on the measurement data, and determining a final optimum duty ratio correction factor from the estimated optimum duty ratio correction factors. The pre-defined duty ratio correction factors may be selected to simplify the calculations for choosing the final optimum duty ratio correction factor. The wireless transmitter can be calibrated by configuring the local oscillator unit based on the final optimum duty ratio correction factor.